Application of Cell lineage (in C.elegans)

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 Application of Cell lineage (in C.elegans)

  • Observe which cells in blastula develop into a cell of a particular tissue or organ of the Embryo. During gastrulation these cells migrate from the existing position to the prospective position
  • Understanding – Gastrulation
  • Classical developmental biology : insight into development process of C.elegans and dorsophilla these organism display in vibrant patterns of cell division in which is specification of cell determination and and highly reproducible and cell -cell interactions.
  • Mutation in cell lineage help us understand mechanisms of fate specification and control of cell proliferation.
  • Stem cell research - provides information about how the behaves in context of intact tissue as opposed to isolation ,  transplantation and invito– culture.
  • Modelling heterogeneity in cancer
  • Can be performed with prior  knowledgeable of what the genes are expressed by cell of  interest.

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